The 2010 Nissan Murano comes equipped with a 3.5-liter VQ35DE V6 engine that produces 265 horsepower and 248 lb-ft of torque. This naturally aspirated engine features dual overhead cams, variable valve timing, and aluminum construction for reduced weight. The VQ35DE is part of Nissan’s acclaimed VQ engine family, known for smooth operation and strong mid-range torque delivery. It’s paired exclusively with a continuously variable transmission (CVT) and available in both front-wheel drive and all-wheel drive configurations. The engine requires regular maintenance including oil changes every 5,000 miles and timing chain inspection around 100,000 miles.

The 2010 Nissan Murano shares most parts with the 2009-2014 model years, as these represent the second generation with minimal changes. Engine components from the 3.5L VQ35DE are largely interchangeable across this range. Body panels, interior trim, and suspension components are generally compatible within this generation. However, there were minor updates in 2011 that affected some electrical components and infotainment systems. The CVT transmission underwent revisions during this period, so transmission parts may have specific year requirements. Always verify part numbers when sourcing components, as running changes within model years can affect compatibility even within the same generation.

Parts availability changes daily. Call us at (603) 392-7313 or visit our online shop to check current inventory from this specific vehicle. If we have sold a part you need, our Parts Broker service can source it from our network of partner yards nationwide.

Yes! We ship parts from this vehicle and our entire inventory nationwide. Most orders ship within 1-2 business days via FedEx or freight carriers for larger components like engines and transmissions. Call (603) 392-7313 for a shipping quote on any part.

The 3.5L VQ35DE engine in the 2010 Murano is generally reliable when properly maintained, though it has some known weak points. The engine itself is robust and can easily exceed 200,000 miles with regular oil changes and timing chain maintenance. However, supporting components like the exhaust manifolds are prone to cracking due to heat cycling. The engine’s main weakness is its pairing with the CVT transmission, which has a poor reliability record. Regular CVT fluid changes every 30,000 miles can help extend transmission life. Overall, the engine is more reliable than the transmission it’s mated to, making it a decent choice for those willing to address the CVT’s maintenance needs proactively.