The 2006 Toyota Sienna comes equipped with a 3.3-liter V6 engine (1MZ-FE), producing 230 horsepower and 242 lb-ft of torque. This naturally aspirated DOHC engine features aluminum construction with iron cylinder liners and Toyota’s VVT-i variable valve timing system. The engine is paired with a 5-speed automatic transmission and is available in both front-wheel drive and all-wheel drive configurations. This powerplant provides adequate performance for family hauling while maintaining reasonable fuel economy of approximately 19 city/26 highway mpg in FWD models.

The 2006 Toyota Sienna shares most parts with the 2004-2010 second-generation Sienna models. Engine components from the 3.3L V6 are largely interchangeable across these years, including intake manifolds, cylinder heads, and most sensors. Body panels, interior trim, and many electrical components are compatible within this generation. However, there were minor updates in 2007 and 2008 that affected some trim pieces and electronic modules. The transmission, suspension components, and brake parts generally interchange well across 2004-2010 models, making salvage parts readily available from this popular generation.

Parts availability changes daily. Call us at (603) 392-7313 or visit our online shop to check current inventory from this specific vehicle. If we have sold a part you need, our Parts Broker service can source it from our network of partner yards nationwide.

Yes! We ship parts from this vehicle and our entire inventory nationwide. Most orders ship within 1-2 business days via FedEx or freight carriers for larger components like engines and transmissions. Call (603) 392-7313 for a shipping quote on any part.

The 3.3L 1MZ-FE engine in the 2006 Sienna is generally reliable and can easily reach 200,000+ miles with proper maintenance. This proven powerplant has been used across multiple Toyota models since the late 1990s. Key maintenance items include regular oil changes every 5,000 miles, timing belt replacement at 90,000-mile intervals, and coolant system service. The engine’s main weakness is the water pump, which should be replaced with the timing belt. Overall, this engine offers good longevity when maintained properly, though it’s not as bulletproof as Toyota’s smaller four-cylinder engines.