The 2010 Honda Odyssey is equipped with Honda’s 3.5L V6 SOHC i-VTEC engine, producing 244 horsepower and 240 lb-ft of torque. This naturally aspirated engine features Variable Cylinder Management (VCM) technology that can deactivate cylinders during light load conditions to improve fuel economy. The engine uses a timing belt that requires replacement every 105,000 miles along with the water pump. It’s paired with a 5-speed automatic transmission and achieves EPA ratings of 17 city/25 highway mpg. The engine requires regular unleaded gasoline and has a 20-gallon fuel tank capacity.

The 2010 Honda Odyssey shares most parts with the 2011-2017 model years, as they’re all part of the fourth generation. The 3.5L V6 engine components are largely interchangeable across these years, though some sensors and emissions components may vary. Body panels, interior trim, and most mechanical parts from 2011-2013 models are direct fits. The 2014-2017 models received a facelift with different front and rear bumpers, headlights, and taillights, but most other parts remain compatible. Transmission parts are generally interchangeable within the 2010-2014 range, while 2015+ models may have slight variations.

Parts availability changes daily. Call us at (603) 392-7313 or visit our online shop to check current inventory from this specific vehicle. If we have sold a part you need, our Parts Broker service can source it from our network of partner yards nationwide.

Yes! We ship parts from this vehicle and our entire inventory nationwide. Most orders ship within 1-2 business days via FedEx or freight carriers for larger components like engines and transmissions. Call (603) 392-7313 for a shipping quote on any part.

The 3.5L V6 in the 2010 Odyssey is generally reliable but has some notable issues. The Variable Cylinder Management system can cause oil consumption problems and carbon buildup, particularly after 80,000 miles. Regular oil changes every 5,000 miles with full synthetic oil help minimize VCM-related issues. The timing belt must be replaced at 105,000 miles to prevent catastrophic engine damage. When properly maintained and driven conservatively, these engines can reach 200,000+ miles. Avoid extended idle periods and consider VCM disable modifications if oil consumption becomes problematic. Overall, it’s a capable engine that requires attentive maintenance.